Original Investigations 106 Association of MTHFR Gene Variants with Autism    Marvin Boris, M.D.; Allan Goldblatt, P.A.;    Joseph Galanko, Ph.D.; S. Jill James, Ph.D. Download article in PDF format Medical Controversies and Analysis 109 The Food Guide Pyramid: Will the Defects be Corrected?    Alice Ottoboni, Ph.D., Fred Ottoboni, M.P.H., Ph.D. Download article in PDF format Commentary 114 Evaluating the Risks of Unwarranted Prosecution, Part I: The Criminalization of Pain Management    Frank B. Fisher, M.D. Download article in PDF format 118 Pre-ingestion Pharmacokinetics: Neglected Variables    Hilton P. Terrell, M.D., Ph.D.,    Kelly W. Jones, Pharm. D. Download article in PDF format 121 Sham Peer Review: a Pathology Report    John R. Minarcik, M.D., Download article in PDF format From The Archives 123 Here I Stand    Jack Schreiber, M.D. Download article in PDF format

Departments 97 Correspondence    Comments from Readers and Authors' Replies       C. Alan B. Clemetson, M.D.; Joel M.Kauffman, Ph.D.;       J. Philip Smith, M.D.; Karen Cosper, R.N.;       Adam Jacobs, M.D.; Matthew Grove, M.D.;       G.S. Goldman, Ph.D.; F.E. Yazbak, M.D.;       Jeffrey A. Trelka; Brian S. Hooker, Ph.D., P.E. Download article in PDF format   102 Editorial: Medicare: Incompetence-Based Bureaucracy    Lawrence R. Huntoon, M.D., Ph.D. Download article in PDF format   105 From the President: The Healthcare Choice Act    Mark Schiller, M.D. Download article in PDF format   125 Book Reviews    Should I Be Tested for Cancer? Maybe Not and    Here's Why (H. Gilbert Welch)       Reviewed by Joel M. Kauffman, Ph.D.    Lives At Risk: Single-Payer National Health    Insurance Around the World (John Goodman,    Gerald Musgrave and Devon Herrick)       Reviewed by Gerry Smedinghoff    Left Illusions (David Horowitz)       Reviewed by Lee Hieb, M.D.    Give Me A Break (John Stossel)       Reviewed by Jerome Arnett, Jr., M.D. Download article in PDF format